Iboga
Neurobloom Iboga · 100 mg
The Tree of Knowledge of the Gabonese Bwiti — a long, lucid waking dream that audits a whole life, interrupts addiction, and reorders the self. The most medically serious doorway we carry, walked with cardiac mastery.
The most serious sacrament in the library
Iboga is the root-bark medicine of Tabernanthe iboga, a shrub of the equatorial forests of Gabon, Cameroon and Congo, and the living centre of the Bwiti tradition that calls it the Tree of Knowledge. Its alkaloid, ibogaine, belongs to no single class — it is an NMDA antagonist, a kappa-opioid agonist, a SERT/DAT inhibitor and a nicotinic antagonist all at once.
A full flood dose does not feel like the classic psychedelics. Rather than visual fireworks it pulls you into a long lucid dream, a panoramic life-review watched with an observer calm. This is its supreme gift — and the reason it demands more preparation than anything else we carry.
The seriousness is not a reason for fear; it is the map for walking the path with care. Ibogaine and its long-lived metabolite noribogaine prolong the heart QT interval, so a real dose belongs under a baseline ECG, corrected electrolytes, prophylactic magnesium and a sober medical sitter. The screening is the medicine done right. This 100 mg capsule is a lower psychospiritual dose; the full flood is a clinical event, never a solo one.
The dose ladder
Anchored to purified ibogaine HCl, dosed by bodyweight. Read this first: root bark, total-alkaloid extract and HCl differ in ibogaine content by roughly sixtyfold and are NEVER interchangeable by weight. Always work from an assay with a Certificate of Analysis, and always take a 2–3 mg/kg test dose at least two hours before any large dose.
The Quiet Companion
Sub-perceptual energy, focus and flow — a cleaner lift than caffeine. Watch for accumulation: because noribogaine is long-lived, repeated micro doses can stack. If the same dose feels stronger over time, stop.
The Navigable Dream
A gentler, shorter introspective and dream-tinged arc with far less overwhelming ataxia. Useful for psychospiritual work without the full multi-day reset. This 100 mg dose sits at the entry of this band — still QT-active.
The Reckoning
The full ego-dissolving life-review and addiction interruption. A clinical event: baseline ECG, electrolyte correction, IV magnesium, continuous telemetry and an ACLS-capable sitter. The Stanford MISTIC protocol used 12.1 mg/kg. Never above 24 mg/kg in 24 hours.
Hard ceilings (GITA guidelines): doses above 12 mg/kg carry higher cardiac-abnormality rates, and cumulative dosing must NEVER exceed 24 mg/kg in any 24-hour period. CYP2D6 poor metabolizers (genetic, or via paroxetine/fluoxetine/quinidine/bupropion/grapefruit) clear ibogaine slowly — consider at least halving the dose. Confusing a TA flood with an HCl flood can be fatal.
What to expect — the waking dream
Iboga is inward and oneiric — a long lucid dream rather than a light show, with a dissociative NMDA character. At flood dose it unfolds in recognizable phases. Sleeplessness for days afterward is a defining feature.
Onset
Effects build gradually — buzzing or vibrating sensations, temperature shifts, heaviness. Nausea is common and often peaks here. Most people lie down and stay down.
Visionary
The waking dream. Closed-eye replays of life events, a panoramic life-review run like a high-speed film, encounters and landscapes, catharsis and an observer calm. Ataxia is most pronounced here — you must lie still in a dark, quiet room.
Evaluative
The vivid imagery recedes into a long, cognitively clear, emotionally neutral period where much of the real re-evaluation of memories, trauma and patterns happens.
Grey tail
Visions gone, but a mild stimulant action keeps you wired and sleepless even while exhausted. A flat low-energy day often lands on day two or three before mood lifts. Hydrate with electrolytes, never plain water, for at least 72 hours.
What it offers
Iboga is not recreational or casual. It is a threshold you cross deliberately, with cardiac mastery in place, to put down a burden and walk out reordered.
Addiction interruption
The flagship use. Observational cohorts report rapid collapse of opioid withdrawal and craving and higher abstinence than conventional detox after a single treatment, extending to cocaine and other substances. The medicine opens the door; aftercare keeps it open.
Trauma, PTSD and depression
The Stanford MISTIC study (30 veterans, 12.1 mg/kg + magnesium) reported, at one month, roughly 88% reductions in PTSD, 87% in depression and 81% in anxiety, with no serious cardiac events — the strongest modern signal that iboga heals trauma, not only addiction.
The neuroplastic window
Noribogaine persists for days and GDNF upregulation can run for weeks, opening a genuine neuroplastic window with a widely cited ~90-day horizon. Treat these weeks as sacred working time across body, mind and environment.
A panoramic audit
Even at psychospiritual doses, the medicine offers an unflinching, observer-eyed review of how one has lived — the kind of reckoning that reorders priorities for years.
The pharmacology, for the curious
A single molecule with an unusually wide receptor footprint — and a long metabolite that keeps the heart in play for days.
01Why the heart is the whole game
Ibogaine and noribogaine block the cardiac hERG potassium channel, delaying repolarization and prolonging QT. After a single 10 mg/kg dose, mean QTc prolongation was about 95 ms and roughly half of subjects transiently exceeded QTc 500 ms. Screened and monitored, that risk is managed; ignored, it can be fatal.
02The long noribogaine tail
Ibogaine itself is short-lived, but it becomes noribogaine, whose 28–49 hour half-life keeps the conduction system stretched for over a day. You cannot safely re-dose a flood the next day, and QT can stay prolonged for up to 7–12 days — cardiac care continues through at least 72 hours.
03The inverted tolerance
Iboga is essentially anti-addictive — not euphoric, very low abuse potential, self-regulating. A single flood resets drug tolerance and quiets cravings for months. The spacing floor is set by cardiac recovery, never by craving.
04The opioid trap
Critically, ibogaine SHARPLY LOWERS opioid tolerance. A post-treatment relapse at a previously normal opioid dose can be fatal. Anyone with an opioid history should know this cold and keep naloxone on hand.
Safety first, always
This is the most medically serious sacrament we carry. Its dangers are real and cardiac-driven — but they are exactly mapped, and that map is the practice. Present the monitoring as mastery, not as fear.
Hard lines — do not combine
Contraindications & care
A doorway crossed with reverence
To honour iboga is to respect its clock and its weight. Screen the heart, correct the electrolytes, load the magnesium, clear the medications, and keep a sober guide at your side. Cross rarely, and only with full cardiac care in place. Walk it this way and iboga gives what it is famous for: a doorway few medicines can match, and a self walked back through reordered.
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